Microwave-Assisted Neat Procedure for the Petasis Reaction
Pierrick Nun, Jean Martinez, Frédéric Lamaty*
*Institut des Biomolécules Max Mousseron, UMR 5247
CNRS-Universités Montpellier 1 et 2, Université Montpellier, 2, Place Eugène
Bataillon, 34095 Montpellier Cedex 05, France, Email: Frederic.lamaty
univ-montp2.fr
P. Nun, J. Martinez, F. Lamaty, Synthesis, 2010, 2063-2068.
DOI: 10.1055/s-0029-1218727
Abstract
Borono-Mannich reactions can be performed in solvent-free conditions under microwave irradition with short reaction time. Full conversion of the starting materials towards the expected product was achieved, starting from stoichiometric quantities of reactants, avoiding column chromatography. No purification step other than an aqueous washing was required.
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Key Words
Petasis Reaction, Microwave Synthesis, Green Chemistry, Multicomponent Reactions, Solvent-Free
ID: J66-Y2010-1670
