Direct Oxidative Conversion of Alcohols, Amines, Aldehydes, and Benzyl Halides into the Corresponding Nitriles with Trichloroisocyanuric Acid in Aqueous Ammonia
*Department of Chemistry, Payame Noor University (PNU), Songhor, Kermanshah, Iran, Email: hojatveisiyahoo.com
H. Veisi, Synthesis, 2010, 2631-2635.
An efficient one-pot conversion of various alcohols, aldehydes and primary amines into the corresponding nitriles in excellent yields was easily achieved by the use of trichloroisocyanuric acid (TCCA) as an oxidant in aqueous ammonia. Also, various benzylic halides were smoothly and directly converted into the corresponding aromatic nitriles in high yields under the same conditions.
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