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Direct Oxidative Conversion of Alcohols, Amines, Aldehydes, and Benzyl Halides into the Corresponding Nitriles with Trichloroisocyanuric Acid in Aqueous Ammonia

Hojat Veisi*

*Department of Chemistry, Payame Noor University (PNU), Songhor, Kermanshah, Iran, Email:

H. Veisi, Synthesis, 2010, 2631-2635.

DOI: 10.1055/s-0029-1218827


An efficient one-pot conversion of various alcohols, aldehydes and primary amines into the corresponding nitriles in excellent yields was easily achieved by the use of trichloro­isocyanuric acid (TCCA) as an oxidant in aqueous ammonia. Also, various benzylic halides were smoothly and directly converted into the corresponding aromatic nitriles in high yields under the same conditions.

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Key Words

trichloroisocyanuric acid, nitriles, alcohols, amines, aldehydes, alkyl halides

ID: J66-Y2010-2100