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Hydroxyterphenylphoshine-Palladium Catalyst for Benzo[b]furan Synthesis from 2-Chlorophenols. Bifunctional Ligand Strategy for Cross-Coupling of Chloroarenes

Jia-Rui Wang and Kei Manabe*

*School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan, Email: manabeu-shizuoka-ken.ac.jp

J.-R. Wang, K. Manabe, J. Org. Chem., 2010, 75, 5340-5342.

DOI: 10.1021/jo1007948 (free Supporting Information)


Abstract

Hydroxyterphenylphosphine is an effective ligand for a Pd-catalyzed one-pot benzo[b]furan synthesis from 2-chlorophenols and alkynes.

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proposed intermediate



Key Words

Benzofurans


ID: J42-Y2010-2180