Asymmetric CuH-Catalyzed 1,4-Reductions in Water at Room Temperature

Shenlin Huang, Karl R. Voigtritter, John B. Unger, Bruce H. Lipshutz*

*Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA, Email: lipshutzchem.ucsb.edu

S. Huang, K. R. Voigtritter, H. B. Unger, B. H. Lipshutz, Synlett, 2010, 2041-2044.

DOI: 10.1055/s-0030-1258540

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Abstract

Taking advantage of micellar catalysis in water, asymmetric hydrosilylation reactions can be conducted at ambient temperatures using water as the global medium.

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Asymmetric 1,4-Hydrosilylations of α,β-Unsaturated Esters

B. H. Lipshutz, J. M. Servesko, B. R. Taft, J. Am. Chem. Soc., 2004, 126, 8352-8353.

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Key Words

copper hydride, PMHS, hydrosilylations, reduction, asymmetric catalysis, micellar catalysis, green chemistry

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ID: J60-Y2010-2320