Stereoselective Syntheses of Trisubstituted Olefins via Platinum Catalysis: α-Silylenones with Geometrical Complementarity
Douglas A. Rooke and Eric M. Ferreira*
*Department of Chemistry, Colorado State University, Fort
Collins, Colorado 80523, Email: emferr
mail.colostate.edu
D. A. Rooke, E. M. Ferreira, J. Am. Chem. Soc., 2010, 132, 11926-11928.
DOI: 10.1021/ja1058197
Abstract
The use of a catalytic amount of PtCl2 enables the conversion of α-hydroxypropargylsilanes to (Z)-silylenones through a highly selective silicon migration via alkyne activation. The complementary (E)-silylenones are accessed by a regioselective hydrosilylation of the ynone precursor.
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Key Words
ID: J48-Y2010-2430
