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Cu-Catalyzed Double S-Alkenylation of Potassium Sulfide: A Highly Efficient Method for the Synthesis of Various Thiophenes

Wei You, Xiaoyu Yan, Qian Liao and Chanjuan Xi*

Key Lab of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China, Email:

W. You, X. Yan, Q. Liao, C. Xi, Org. Lett., 2010, 12, 3930-3933.

DOI: 10.1021/ol101619s


Copper-catalyzed tandem S-alkenylation of potassium sulfide with 1,4-diiodo-1,3-dienes enables an efficient synthetic approach to variously substituted thiophenes.

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ID: J54-Y2010-2530