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Facile Epoxidation of α,β-Unsaturated Ketones with trans-3,5-Dihydroperoxy-3,5-dimethyl-1,2-dioxolane as an Efficient Oxidant

Davood Azarifar*, Kaveh Khosravi

*Faculty of Chemistry, Buali Sina University, Hamedan 65178, Iran, Email:

D. Azarifar, K. Khosravi, Synlett, 2010, 2755-2758.

DOI: 10.1055/s-0030-1258996


The epoxidation of trans-chalcones proceeds under mild conditions at room temperature in alkaline solution to afford the corresponding epoxides in excellent yields using trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane as an efficient oxygen source.

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Key Words

α,β-unsaturated ketone, epoxides, dihydroperoxides, trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane, epoxidation

ID: J60-Y2010-3050