Cu(OTf)2-Mediated Chan-Lam Reaction of Carboxylic Acids to Access Phenolic Esters
Lingli Zhang, Guoying Zhang, Manli Zhang and Jiang Cheng*
*College of Chemistry and Materials Engineering, Wenzhou
University, Wenzhou 325027, People's Republic of China, Email: jiangcheng
wzu.edu.cn
L. Zhang, G. Zhang, M. Zhang, J. Cheng, J. Org. Chem., 2010, 75, 7472-7474.
DOI: 10.1021/jo101558s
Abstract
A Cu(OTf)2-mediated Chan-Lam reaction of carboxylic acids with arylboronic acids is a facile and practical methodology to access phenolic esters in good yields. The procedure tolerates various functional groups, such as methoxycarbonyl, acetoxy, free phenolic hydroxyl, vinyl, nitro, trifluoromethyl, methoxyl, bromo, chloro, iodo, and acetyl groups.
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Key Words
Chan-Lam Coupling, Phenols, Esters
ID: J42-Y2010-3080
