Gold(I)-Catalyzed Addition of Carboxylic Acids to Alkynes

Bathoju Chandra Chary and Sunggak Kim*

*Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore, Email: sgkimntu.edu.sg

B. C. Chary, S. Kim, J. Org. Chem., 2010, 75, 7928-7931.

DOI: 10.1021/jo101543q

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Abstract

PPh₃AuCl/AgPF₆-catalyzed hydroacyloxylation of alkynes with carboxylic acids affords the Markonikov addition products, whereas PPh₃AuCl/AgOTf catalyst gives the more stable isomerized products via the Markonikov products.

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Key Words

Esters, Carbonyl Compounds, Enols

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ID: J42-Y2010-3240