Fast, Efficient, Mild, and Metal-Free Synthesis of Pyrroles by Domino Reactions in Water
Magnus Rueping* and Alejandro Parra
*Institute of Organic Chemistry, RWTH Aachen University,
Landoltweg 1, D-52074 Aachen, Germany, Email: magnus.rueping
rwth-aachen.de
M. Rueping, A. Parra, Org. Lett., 2010, 12, 5281-5283.
DOI: 10.1021/ol102247n
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Abstract
A fast, mild, and environmentally benign domino reaction enables an efficient reaction of (E)-β-bromonitrostyrenes with enaminones in water to afford pyrroles in excellent yields.
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Key Words
Pyrroles, Green Chemistry, Enaminones
ID: J54-Y2010-3250
