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A Concise Access to 3-Substituted 2-Pyrones

Frédéric Frébault, Maria Teresa Oliveira, Eckhard Wöstefeld and Nuno Maulide*

*Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany, Email: maulidempi-muelheim.mpg.de

F. Frébault, M. T. Oliveira, E. Wöstefeld, Nuno Maulide, J. Org. Chem., 2010, 75, 762-7695.

DOI: 10.1021/jo101843a (free Supporting Information)


Abstract

An electrophilic pyrone derivative, which can be readily prepared on a multigram scale, undergoes metal-catalyzed cross-coupling reactions with a variety of nucleophiles to yield 3-substituted-2-pyrones.


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Key Words

2-pyrones


ID: J42-Y2010-3280