La(OTf)3: An Efficient Promoter for Thioglycoside Activation in Conjunction with N-Iodosuccinimide
Somnath Mukherjee, Balaram Mukhopadhyay*
*Department of Chemical Sciences, Indian Institute of Science
Education and Research-Kolkata, Mohanpur Campus, BCKV Main Campus, Mohanpur,
Nadia 741 252, West Bengal, India, Email: sugarnet73
hotmail.com
S. Mukherjee, B. Mukhopadhyay, Synlett, 2010, 2853-2856.
DOI: 10.1055/s-0030-1259016
Abstract
Use of La(OTf)3 as a Lewis acid promoter for N-iodosuccinimide-mediated activation of thioglycosides enables a smooth glycosylation reaction with good to excellent yields and stereoselectivity.
see article for more examples
Key Words
acetals, oxathioacetals, thioglycosides, glycosylation, disarmed donor, Lewis acid, NIS
ID: J60-Y2010-3310
