Samarium-Promoted Michael Addition between Aroyl Chlorides and Chalcones
Yongjun Liu, Yuanying Li, Yan Qi, Jun Wan*
*State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. of China, Email: wanjundzsohu.com
Y. Liu, Y. Li, Y. Qi, J. Wan, Synthesis, 2010, 4188-4192.
A Michael addition type reaction between aroyl chlorides and chalcones was realized in the presence of samarium metal in N,N-dimethylformamide as solvent. Various 1,4-diketones were synthesized in moderate to good yields. A possible mechanism is also discussed.
see article for more examples
samarium, Michael addition, aroyl chlorides, chalcones, 1,4-diketones