Copper(I) Iodide-Catalyzed Synthesis of 4-Aryl-1H-1,2,3-triazoles from anti-3-Aryl-2,3-dibromopropanoic Acids and Sodium Azide

Yubo Jiang, Chunxiang Kuang*, Qing Yang

*Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, P. R. of China, Email: kuangcxtongji.edu.cn

Y. Jiang, C. Kuang, Q. Yang, Synthesis, 2010, 4256-4260.

DOI: 10.1055/s-0030-1258312

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Abstract

4-Aryl-1H-1,2,3-triazoles were synthesized from anti-3-aryl-2,3-dibromopropanoic acids and sodium azide by using inexpensive copper(I) iodide as the catalyst in the presence of cesium carbonate as base and DMSO as solvent.

see article for more examples

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Copper(I) Iodide Catalyzed Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from anti-3-Aryl-2,3-dibromopropanoic Acids and Organic Azides

X. Chen, Y. Yang, C. Kuang, Q. Yang, Synlett, 2011, 2907-2912.

Palladium-Catalyzed One-Pot Synthesis of 4-Aryl-1H-1,2,3-triazoles from anti-3-Aryl-2,3-dibromopropanoic Acids and Sodium Azide

W. Zhang, C. Kuang, Q. Yang, Synthesis, 2010, 283-287.

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Key Words

1H-1,2,3-triazole, 1,2,3-triazoles, anti-3-aryl-2,3-dibromopropanoic acids, sodium azide, one-pot

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ID: J66-Y2010-3500