An Eco-Sustainable Erbium(III) Triflate Catalyzed Formation and Cleavage of tert-Butyl Ethers
Antonio Procopio*, Paola Costanzo, Massimo Curini, Monica Nardi, Manuela Oliverio, Rosina Paonessa
*Dipartimento Farmaco-Biologico, Universitą degli Studi della Magna Gręcia Complesso Ninģ Barbieri, 88021 Roccelletta di Borgia (CZ), Italy, Email: procopiounicz.it
A. Procopio, P. Costanzo, M. Curini, M. Nardi, M. Oliverio, R. Paonessa, Synthesis, 2011, 73-78.
An eco-compatible method for the formation of tert-butyl ethers of alcohols and phenols is performed in solvent-free conditions at room temperature using catalytic amount of Er(OTf)3. The catalyst is easily recovered and reused several times without loss of activity. In addition, the tert-butyl group is removed very quickly from alcohols and phenols in methanol in the presence of Er(OTf)3 using MW irradiation.
see article for more examples