Direct Conversion of Olefins into α-Bromo Ketones Using O-Iodoxybenzoic Acid and Tetraethylammonium Bromide
Swapnil S. Deshmukh, Kiran H. Chaudhari, Krishnacharya G. Akamanchi*
*Department of Pharmaceutical Sciences and Technology,
Institute of Chemical Technology, Matunga, Mumbai 400019, India, Email: kgap
rediffmail.com
S. S. Deshmukh, K. H. Chaudhari, K. G. Akamanchi, Synlett, 2011, 81-83.
DOI: 10.1055/s-0030-1259090
Abstract
Utilizing the full potential of IBX, a mild, selective, and facile method enables a direct conversion of olefins into the corresponding α-bromo ketones in the presence of 1.1 equivalents each of o-iodoxybenzoic acid and tetraethylammonium bromide.
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Key Words
o-iodoxybenzoic acid, tetraethylammonium bromide, α-bromo ketones, carbonyl compounds
ID: J60-Y2011-0030
