DABCO-Catalyzed Oxidation of Deoxybenzoins to Benzils with Air and One-Pot Synthesis of Quinoxalines
Chaorong Qi, Huanfeng Jiang*, Liangbin Huang, Zhengwang Chen, Huoji Chen
*School of Chemistry and Chemical Engineering, South China
University of Technology, 381 Wushan Road, Guangzhou 510640, P. R. of China, Email:
jianghf
scut.edu.cn
C. Qi, H. Jiang, L. Huang, Z. Chen, H. Chen, Synthesis, 2011, 387-396.
DOI: 10.1055/s-0030-1258375
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Abstract
Aerobic oxidation of deoxybenzoins is efficiently catalyzed by 1,4-diazabicyclo[2.2.2]octane (DABCO) with air as the sole oxidant to give the corresponding benzils in excellent yields. The process has been successfully extended to a one-pot synthesis of quinoxalines from benzyl ketones and aromatic 1,2-diamines.
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Key Words
deoxybenzoins, benzils, 1,2-diketones, oxidation, oxygen, 1,2-diamines, quinoxalines
ID: J66-Y2011-0240
