Facile Synthesis of (E)-Alkenyl Aldehydes from Allyl Arenes or Alkenes via Pd(II)-Catalyzed Direct Oxygenation of Allylic C-H Bond
Huoji Chen, Huanfeng Jiang*, Congbi Cai, Jia Dong and Wei Fu
*School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China, Email: jianghfscut.edu.cn
H. Chen, H. Jiang, C. Cai, J. Dong, W. Fu, Org. Lett., 2011, 13, 992-994.
DOI: 10.1021/ol1030316 (free Supporting Information)
Palladium-catalyzed oxygenation of allyl arenes or alkenes produce (E)-alkenyl aldehydes with high yields. Allylic C-H bond cleavages occur under mild conditions during this process. Mechanistic studies show that oxygen source is water.
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