Organic Chemistry Portal

Abstracts

Search:

Gold-Catalyzed Direct Amination of Arenes with Azodicarboxylates

Liuqun Gu, Boon Siong Neo and Yugen Zhang

*Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, the Nanos, Singapore 138669, Email: ygzhangibn.a-star.edu.sg

L. Gu, B. S. Neo, Y. Zhang, Org. Lett., 2011, 13, 1872-1874.

DOI: 10.1021/ol200373q (free Supporting Information)


see article for more reactions

Abstract

A gold(III) chloride catalyzed direct amination of arenes with azodicarboxylates allows the conversion of a broad range of substrates, including electron-deficient arenes, under mild conditions. This reaction provides an important approach for the synthesis of heterocyclic compounds in pharmaceutical and chemical industries.

see article for more examples



Key Words

Hydrazides


ID: J54-Y2011-0930