Highly Stereoselective Facile Synthesis of 2-Acetoxy-1,3(E)-alkadienes via a Rh(I)-Catalyzed Isomerization of 2,3-Allenyl Carboxylates
Xiaobing Zhang, Chunling Fu, and Shengming Ma*
*Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, Zhejiang, People’s Republic of China, Email: masmsioc.ac.cn
X. Zhang, C. Fu, S. Ma, Org. Lett., 2011, 13, 1920-1923.
DOI: 10.1021/ol200198z (free Supporting Information)
A highly stereoselective Rh(I)-catalyzed 1,3-acetoxyl rearrangement of 1,2-allen-3-yl carboxylates leads to 2-acetoxy-1,3(E)-alkadienes. Features of the reaction are a high catalytic efficiency, broad scope and excellent E-selectivity.
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