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An Efficient Phosphine-Free Heck Reaction in Water Using Pd(L-Proline)2 as the Catalyst Under Microwave Irradiation

Bharat Kumar Allam, Krishna Nand Singh*

*Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi-221005, India, Email:

B. K. Allam, K. N. Singh, Synthesis, 2011, 1125-1131.

DOI: 10.1055/s-0030-1258452

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An efficient and simple protocol for phosphine-free Heck reactions in water in the presence of a Pd(L-proline)2 complex as the catalyst under controlled microwave irradiation conditions is versatile and provides excellent yields of products in short reaction times. The reaction system minimizes costs, operational hazards and environmental pollution.

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Key Words

Heck reaction, palladium, Pd(L-proline)2, microwave synthesis, phosphine-free, green chemistry

ID: J66-Y2011-1000