Highly Chemoselective Esterification Reactions and Boc/THP/TBDMS Discriminating Deprotections under Samarium(III) Catalysis
Pushparathinam Gopinath, Surapaneni Nilaya and Kannoth Manheri Muraleedharan*
*Department of Chemistry, Indian Institute of Technology Madras, Chennai, 600 036, India, Email: mkmiitm.ac.in
P. Gopinath, S. Nilaya, K. M. Muraleedharan, Org. Lett., 2011, 13, 1932-1935.
DOI: 10.1021/ol200247c (free Supporting Information)
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SmCl3 is an excellent catalyst for chemoselective esterifications and selective removal of acid sensitive hydroxyl protecting groups such as Boc, THP, and TBDMS. Chemoselective deprotection is demonstrated through suitable examples.
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