Cu(I)-Catalyzed Domino Reactions: Efficient and Selective Synthesis of 4H-Chromenes and Naphthalenes
Chandi C. Malakar, Dietmar Schmidt, Jürgen Conrad and Uwe Beifuss*
*Institut fur Chemie, Universitat Hohenheim, Garbenstr. 30,
70599 Stuttgart, Germany, Email: ubeifussuni-hohenheim.de
C. C. Malakar, D. Schmidt, J. Conrad, U. Beifuss, Org. Lett., 2011, 13, 1972-1975.
DOI: 10.1021/ol200347g (free Supporting Information)
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Abstract
A Cu(I)-catalyzed domino reaction between bromobenzyl bromides and β-ketoesters exclusively yields either 4H-chromenes or naphthalenes depending on the ratio of the substrates and the reaction conditions.
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Key Words
ID: J54-Y2011-1040