Organic Chemistry Portal

Abstracts

Search:

Copper-Catalyzed Trifluoromethylation of Aryl and Vinyl Boronic Acids with An Electrophilic Trifluoromethylating Reagent

Tianfei Liu and Qilong Shen*

*Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, People's Republic of China, Email: shenqlmail.sioc.ac.cn

T. Liu, Q. Shen, Org. Lett., 2011, 13, 2342-2345.

DOI: 10.1021/ol2005903


Abstract

A copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with Togni's reagent proceeded in good to excellent yields for a range of different substrates including heteroarylboronic acids and substrates with a variety of functional groups under mild reaction conditions.

see article for more examples



Key Words

trifluoromethylation of arenes


ID: J54-Y2011-1340