N-Bromosuccinimide Initiated One-Pot Synthesis of Imidazoline
Ling Zhou, Jing Zhou, Chong Kiat Tan, Jie Chen and Ying-Yeung Yeung*
*Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Email: yyyeungcuhk.edu.hk
L. Zhou, J. Zhou, C. K. Tan, J. Chen, Y.-Y. Yeung, Org. Lett., 2011, 13, 2448-2451.
DOI: 10.1021/ol2006902 (free Supporting Information)
A novel cationic Br initiated one-pot synthesis using olefin, nitrile, amine, and N-bromosuccinimide gives imidazolines in good yields. The olefinic substrates and the nitrile partners can be flexibly varied to achieve a range of imidazoline derivatives.
see article for more examples
L. Zhou, J. Chen, J. Zhou, Y.-Y. Yeung, Org. Lett., 2011, 13, 5804-5807.