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N-Bromosuccinimide Initiated One-Pot Synthesis of Imidazoline

Ling Zhou, Jing Zhou, Chong Kiat Tan, Jie Chen and Ying-Yeung Yeung*

*Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Email:

L. Zhou, J. Zhou, C. K. Tan, J. Chen, Y.-Y. Yeung, Org. Lett., 2011, 13, 2448-2451.

DOI: 10.1021/ol2006902


A novel cationic Br initiated one-pot synthesis using olefin, nitrile, amine, and N-bromosuccinimide gives imidazolines in good yields. The olefinic substrates and the nitrile partners can be flexibly varied to achieve a range of imidazoline derivatives.

see article for more examples

N-Bromosuccinimide Promoted One-Pot Synthesis of Guanidine: Scope and Mechanism

L. Zhou, J. Chen, J. Zhou, Y.-Y. Yeung, Org. Lett., 2011, 13, 5804-5807.

Key Words

Imidazolines, N-Bromosuccinimide, Multicomponent Reaction

ID: J54-Y2011-1420