Organic Chemistry Portal



Fluorenone Synthesis by Palladacycle-Catalyzed Sequential Reactions of 2-Bromobenzaldehydes with Arylboronic Acids

Tao-Ping Liu, Yuan-Xi Liao, Chun-Hui Xing and Qiao-Sheng Hu*

*Department of Chemistry, College of Staten Island and the Graduate Center of the City University of New York, Staten Island, New York 10314, United States, Email:

T.-P. Liu, Y.-X. Liao, C.-H. Xing, Q.-S. Hu, Org. Lett., 2011, 13, 2452-2455.

DOI: 10.1021/ol200693d


A new, anionic four-electron donor-based (type I) palladacycle-catalyzed sequential reaction of 2-bromobenzaldehydes with arylboronic acids based on the addition reaction, cyclization via C-H activation-oxidation sequence provides an efficient access to a variety of substituted fluorenones/indenofluorenediones from readily available starting materials.

see article for more examples

Key Words


ID: J54-Y2011-1430