Fluorenone Synthesis by Palladacycle-Catalyzed Sequential Reactions of 2-Bromobenzaldehydes with Arylboronic Acids
Tao-Ping Liu, Yuan-Xi Liao, Chun-Hui Xing and Qiao-Sheng Hu*
*Department of Chemistry, College of Staten Island and the Graduate Center of the City University of New York, Staten Island, New York 10314, United States, Email: qiaosheng.hucsi.cuny.edu
T.-P. Liu, Y.-X. Liao, C.-H. Xing, Q.-S. Hu, Org. Lett., 2011, 13, 2452-2455.
DOI: 10.1021/ol200693d (free Supporting Information)
A new, anionic four-electron donor-based (type I) palladacycle-catalyzed sequential reaction of 2-bromobenzaldehydes with arylboronic acids based on the addition reaction, cyclization via C-H activation-oxidation sequence provides an efficient access to a variety of substituted fluorenones/indenofluorenediones from readily available starting materials.
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