Copper(I)-Catalyzed Synthesis of Pyrazoles from Phenylhydrazones and Dialkyl Ethylenedicarboxylates in the Presence of Bases
Chaowei Ma, Yanmei Li, Ping Wen, Rulong Yan, Zhiyong Ren, Guosheng Huang*
*State Key Laboratory of Applied Organic Chemistry, Lanzhou
University, Lanzhou 730000, P. R. of China, Email: hgs
lzu.edu.cn
C. Ma, Y. Li, P. Wen, R. Yan, Z. Ren, G. Huang, Synlett, 2011, 1321-1323.
DOI: 10.1055/s-0030-1260522
Abstract
An easy and efficient copper-catalyzed reaction for the synthesis of polysubstituted pyrazoles from phenylhydrazones and dialkyl ethylenedicarboxylates tolerates a range of functionalities, and the corresponding adducts can be obtained in moderate to good yields.
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Key Words
heterocycles, copper catalysis, hydrazones, dialkyl ethylenedicarboxylates, pyrazoles
ID: J60-Y2011-1680
