Ruthenium-Catalyzed Hydrovinylation of N-Acetylenamines Leading to Amines with a Quaternary Carbon Center
Qiu-Shi Wang, Jian-Hua Xie, Wei Li, Shou-Fei Zhu, Li-Xin Wang and Qi-Lin Zhou*
*State Key Laboratory and Institute of Elemento-organic
Chemistry, Nankai University, Tianjin 300071, China, Email: qlzhou
nankai.edu.cn
Q.-S. Wang, J.-H. Xie, W. Lei, S.-F. Zhu, L.-X. Wang, Q.-L. Zhou, Org. Lett., 2011, 13, 3388-3391.
DOI: 10.1021/ol201142v
Abstract
A hydrovinylation of N-acetylenamines with ethylene is catalyzed by a ruthenium hydride complex, RuHCl(CO)(PCy3)2, providing a series of N-acetylamines with a quaternary carbon center with up to 99% yield.
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ID: J54-Y2011-1890
