Synthesis of Unsymmetrical Sulfides Using Ethyl Potassium Xanthogenate and Recyclable Copper Catalyst under Ligand-Free Conditions
Vijay Kumar Akkilagunta and Rama Rao Kakulapati*
*Organic Chemistry Division-I, Indian Institute of Chemical
Technology, Uppal Road, Tarnaka, Hyderabad 500607, India,
Email: kakulapatirama
gmail.com
V. K. Akkilagunta, R. R. Kakulapati, J. Org. Chem., 2011, 76, 6819-6824.
DOI: 10.1021/jo200793k
Abstract
Cross-coupling of inexpensive ethyl potassium xanthogenate with aryl halides using recyclable CuO nanoparticles under ligand-free conditions followed by hydrolysis of the resulting xanthogenate ester and a subsequent cross coupling enables a synthesis of unsymmetrical sulfides in good to excellent yields. The copper oxide nanoparticles can be recovered and reused up to five cycles without loss of activity.
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ID: J42-Y2011-2270
