A Facile Synthesis of α-Fluoro Ketones Catalyzed by [Cp*IrCl2]2
Nanna Ahlsten, Agnieszka Bartoszewicz, Santosh Agrawal, Belén Martín-Matute*
*Department of Organic Chemistry, The Arrhenius Laboratory, Stockholm University, 106 91 Stockholm, Sweden, Email: belenorgan.su.se
N. Ahlsten, A. Bartoszewicz, S. Agrawal, B. Martín-Matute, Synthesis, 2011, 2600-2608.
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Allylic alcohols are isomerized into enolates (enols) by [Cp*IrCl2]2. A subsequent reaction with Selectfluor present in the reaction media produces α-fluoro ketones as single constitutional isomers in good yields.
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