Metal-Free Chlorodeboronation of Organotrifluoroborates
Gary A. Molander* and Livia N. Cavalcanti
*Roy and Diana Vagelos Laboratories, Department of Chemistry,
University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States,
Email: gmolandr
sas.upenn.edu
G. A. Molander, L. N. Cavalcanti, J. Org. Chem., 2011, 76, 7195-7203.
DOI: 10.1021/jo201313a
Abstract
A mild and metal-free method for the chlorodeboronation of organotrifluoroborates using trichloroisocyanuric acid (TCICA) converts aryl-, heteroaryl-, alkenyl-, alkynyl-, and alkyltrifluoroborates into the corresponding chlorinated products in good yields. This method tolerates a broad range of functional groups.
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Key Words
aryl chlorides, alkenyl chlorides, alkynyl chlorides, alkyl chlorides, trichloroisocyanuric acid
ID: J42-Y2011-2480
