Copper(I) Iodide Catalyzed Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from anti-3-Aryl-2,3-dibromopropanoic Acids and Organic Azides
Xuezhi Cheng, Yiwen Yang, Chunxiang Kuang*, Qing Yang*
*Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, P. R. of China, Email: kuangcxtongji.edu.cn, yangqing68fudan.edu.cn
X. Chen, Y. Yang, C. Kuang, Q. Yang, Synthesis, 2011, 2907-2912.
DOI: 10.1055/s-0030-1261030 (free Supporting Information)
In the presence of inexpensive copper (I) iodide as the catalyst, a series of 1,4-disubstituted 1,2,3-triazoles were synthesized in a one-pot process from anti-3-aryl-2,3-dibromopropanoic acids and organic azides in dimethyl sulfoxide.
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Y. Jiang, C. Kuang, Q. Yang, Synthesis, 2010, 4256-4260.
cyclizations, heterocycles, azides, triazoles