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An Improved Palladium-Catalyzed Conversion of Aryl and Vinyl Triflates to Bromides and Chlorides

Jun Pan, Xinyan Wang, Yong Zhang and Stephen L. Buchwald*

*Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States, Email: sbuchwalmit.edu

J. Pan, X. Wang, Y. Zhang, S. L. Buchwald, Org. Lett., 2011, 13, 4974-4976.

DOI: 10.1021/ol202098h (free Supporting Information)


Abstract

A facile Pd-catalyzed conversion of aryl and vinyl triflates allows convenient access to various aryl, heteroaryl, and vinyl halides in good to excellent yields and with greatly simplified conditions relative to our previous report.


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Key Words

aryl bromides, aryl chlorides, vinyl bromides, vinyl chlorides


ID: J54-Y2011-2780