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N-Heterocyclic Carbene/Pd(II)/1-Methylimidazole Complex Catalyzed Suzuki-Miyaura Coupling Reaction of Aryl Chlorides in Water

Xia-Xia Zhou, Li-Xiong Shao*

*College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, P. R. of China, Email:

X.-X. Zhou, L.-X. Shao, Synthesis, 2011, 3138-3142.

DOI: 10.1055/s-0030-1260169


A well-defined, highly active N-heterocyclic carbene (NHC)/palladium chloride/imidazole catalyst enabled the Suzuki-Miyaura coupling reactions of aryl or heteroaryl chlorides in very good yields in water.

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Key Words

N-heterocyclic carbenes, palladium, imidazole, Suzuki coupling, water, green chemistry, biaryls

ID: J66-Y2011-2840