An Efficient and General Method for the Heck and Buchwald-Hartwig Coupling Reactions of Aryl Chlorides
Dong-Hwan Lee, Abu Taher, Shahin Hossain and Myung-Jong Jin*
*Department of Chemical Science and Engineering, Inha University, Incheon 402-751, South Korea, Email: mjjininha.ac.kr
D.-H. Lee, A. Taher, S. Hossain, M.-J. Jin, Org. Lett., 2011, 13, 5540-5543.
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A β-diketiminatophosphane Pd complex acted as a powerful catalyst for the Heck coupling of various aryl chlorides with alkenes under relatively mild conditions. Furthermore, this catalytic system also proved to be highly active in the Buchwald-Hartwig coupling of deactivated and sterically hindered aryl chlorides at room temperature.
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J. P. Sambuli, S. R. Stauffer, K. H. Shaughnessy, J. F. Hartwig, J. Am. Chem. Soc., 2001, 123, 2677-2678.