A Mild Ligand-Free Iron-Catalyzed Liberation of Alcohols from Allylcarbonates
André P. Dieskau and Bernd Plietker*
*Institut für Organische Chemie, FB Chemie, Universität
Stuttgart, Pfaffenwaldring 55, D-70569 Stuttgart, Germany,
Email: bernd.plietker
oc.uni-stuttgart.de
A. P. Dieskau, B. Plietker, Org. Lett., 2011, 13, 5544-5547.
DOI: 10.1021/ol202270g
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Abstract
Different from most carbonates the allyloxy carbonyl protecting group can be cleaved under neutral conditions using expensive precious metals catalysts. Two new Fe-catalyzed protocols enable a mild liberation of alcohols from allylcarbonates, broad functional group tolerance, and exclusive chemoselectivity.
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Key Words
ID: J54-Y2011-3050
