Highly Efficient Copper- and Palladium-Free One-Pot Coupling of Alkynes with Sodium Carboxylate Salts Using Cyanuric and Magnesium Chlorides
Mohammad Navid Soltani Rad*, Somayeh Behrouz*
*Department of Chemistry, Shiraz University of Technology,
Shiraz 71555-313, Iran, Email: soltani
sutech.ac.ir, behrouzsutech.ac.ir
M. N. S. Rad, S. Behrouz, Synlett, 2011, 2562-2566.
DOI: 10.1055/s-0030-1260336
Abstract
The presence of magnesium chloride, cyanuric chloride, and triethylamine enables a highly efficient copper- and palladium-free cross-coupling of terminal alkynes with structurally diverse sodium carboxylate salts to furnish the corresponding ynones in very good yields at room temperature.
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Key Words
one-pot synthesis, alkynes, cyanuric chloride, sodium carboxylate salts, ynones
ID: J60-Y2011-3090
