A Mild and Efficient Route to 2-Azetidinones Using the Cyanuric Chloride-DMF Complex
Maaroof Zarei, Aliasghar Jarrahpour*
*Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran, Email: jarrahsusc.ac.ir
M. Zarei, A. Jarrahpour, Synlett, 2011, 2572-2576.
DOI: 10.1055/s-0030-1289517 (free Supporting Information)
Efficient conversion of Schiff bases and carboxylic acids to β-lactams can be carried out at room temperature in CH2Cl2, using a cyanuric chloride-N,N-dimethyl formamide complex. The complex is easily prepared by reaction of cyanuric chloride and DMF at room temperature.
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