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Ruthenium-Catalyzed Ortho-Alkenylation of Aromatic Ketones with Alkenes by C-H Bond Activation

Kishor Padala and Masilamani Jeganmohan*

*Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India, Email:

K. Padala, M. Jeganmohan, Org. Lett., 2011, 13, 6144-6147.

DOI: 10.1021/ol202580e (free Supporting Information)

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A ruthenium-catalyzed chelation-assisted C-H bond activation of aromatic ketones followed by reaction with olefins provides Heck-type products in good to excellent yields with a high regio- and stereoselective manner.

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Key Words

olefination, unsaturated compounds

ID: J54-Y2011-3390