A Thiophosphoryl Chloride Assisted Transformation of Arylaldoximes to Thioamides
Lokesh Kumar Pandey, Uma Pathak*, Sweta Mathur, M. V. S. Suryanarayana
*Synthetic Chemistry Division, Defence Research & Development Establishment, Gwalior (MP) 474 002, India, Email: sc_drderediffmail.com
L. K. Pandey, U. Pathak, S. Mathur, M. V. S. Suryanarayana, Synthesis, 2012, 44, 272-282.
DOI: 10.1055/s-0031-1289994
Abstract
A sequential tandem approach using thiophosphoryl chloride as a dehydrating and thionating agent enables the conversion of benzaldehyde oximes into primary benzothioamides via benzonitriles.
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U. Pathak, L. K. Pandey, R. Tank, J. Org. Chem., 2008, 73, 2890-2893.
Key Words
primary thioamides, oximes, thiophosphoryl chloride, nitriles
ID: J66-Y2012-0200