Ligand-Free Ni-Catalyzed Reductive Cleavage of Inert Carbon-Sulfur Bonds
Nekane Barbero and Ruben Martin*
*Institute of Chemical Research of Catalonia (ICIQ), Av Pa´sos Catalans 16, 43007, Tarragona, Spain, Email: rmartinromoiciq.es
N. Barbero, R. Martin, Org. Lett., 2012, 14, 796-799.
DOI: 10.1021/ol2033306 (free Supporting Information)
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A catalytic reductive cleavage of C(sp2)- and C(sp3)-SMe bonds under ligandless conditions offers a wide scope and high chemoselectivity profile including challenging substrate combinations, allowing the design of orthogonal and site-selectivity approaches.
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