Palladium-Catalyzed Oxidative Heck Coupling Reaction for Direct Synthesis of 4-Arylcoumarins Using Coumarins and Arylboronic Acids
Yaming Li*, Zisong Qi, Huifeng Wang, Xinmei Fu and Chunying Duan*
*State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, China, Email: ymlidlut.edu.cn, cyduandlut.edu.cn
Y. Li, Z. Qi, H. Wang, X. Fu, C. Duan, J. Org. Chem., 2012, 77, 2053-2057.
Palladium-catalyzed oxidative Heck coupling reaction of coumarins and arylboronic acids allows a direct synthesis of 4-arylcoumarins in good yields. The reaction also showed tolerance toward functional groups such as hydro, methoxy, diethylamino, nitro, and chloro groups.
see article for more examples
coumarins, oxidative Heck reaction, oxygen