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N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex Catalyzed α-Arylation of Ketones with Aryl Chlorides

Zheng-Kang Xiao, Li-Xiong Shao*

*College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, P. R. of China, Email:

Z.-K. Xiao, L.-X. Shao, Synthesis, 2012, 44, 711-716.

DOI: 10.1055/s-0031-1289698


An easily available NHC-Pd(II)-Im complex is an efficient catalyst for the α-arylation reaction between ketones and aryl chlorides. Under the optimal conditions, all reactions proceeded smoothly to give the desired products in very good yields within hours.

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Key Words

N-heterocyclic carbenes, palladium, α-arylation, aryl chlorides, ketones

ID: J66-Y2012-0740