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Iodine-Mediated Intramolecular Oxidative Cyclization of 2-(Styrylthio)anilines: Synthesis of 2-Substituted Benzothiazoles

Dong-Yun Zhao, Xiao-Kang Guo, Jin-Heng Li*, Ri-Yuan Tang

*College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. of China, Email: jhlihnu.edu.cn

D.-Y. Zhao, X.-K. Guo, J.-H. Li, R.-Y. Zang, Synthesis, 2012, 44, 927-933.

DOI: 10.1055/s-0031-1289692


Abstract

A novel metal-free iodine-mediated intramolecular oxidative cyclization protocol allows the preparation of various 2-substituted benzothiazoles.

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Key Words

iodine, oxidation, cyclization, 2-(styrylthio)anilines, benzothiazoles


ID: J66-Y2012-0810