Organic Chemistry Portal



Synthesis of a Wide Range of Thioethers by Indium Triiodide Catalyzed Direct Coupling between Alkyl Acetates and Thiosilanes

Yoshihiro Nishimoto, Aya Okita, Makoto Yasuda and Akio Baba*

*Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan, Email:

Y. Nishimoto, A. Okita, M. Yasuda, A. Baba, Org. Lett., 2012, 14, 1846-1849.

DOI: 10.1021/ol300450j


An efficient, indium triiodide-catalyzed substitution of the acetoxy group in alkyl, benzyl, allyl, and propargyl acetates with thiosilanes provides access to various thioethers.

see article for more examples

Key Words

aryl sulfides, alkyl sulfides, benzyl sulfides, allyl sulfides

ID: J54-Y2012-1030