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Iron-Promoted Tandem Reaction of Anilines with Styrene Oxides via C-C Cleavage for the Synthesis of Quinolines

Yicheng Zhang, Min Wang, Pinhua Li and Lei Wang*

Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, P.R. China, Email:

Y. Zhang, M. Wang, P. Li, L. Wang, Org. Lett., 2012, 14, 2206-2209.

DOI: 10.1021/ol300391t


An iron-promoted tandem reaction of anilines with styrene oxides via C-C cleavage and C-H activation utilizes inexpensive FeCl3 as promoter and is suitable for forming various 3-arylquinolines from simple and readily available starting materials.

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ID: J54-Y2012-1270