1,2,3-Triazole: Unique Ligand in Promoting Iron-Catalyzed Propargyl Alcohol Dehydration
Wuming Yan, Xiaohan Ye, Novruz G. Akhmedov, Jeffrey L. Petersen and Xiaodong Shi*
*C. Eugene Bennett Department of Chemistry, West Virginia
University, Morgantown, West Virginia 26506, United States, Email: xmshi
usf.edu
W. Yan, X. Ye, N. G. Akhmedov, J. L. Petersen, X. Shi, Org. Lett., 2012, 14, 2358-2361.
DOI: 10.1021/ol300778e
Abstract
A 1,2,3-triazole-promoted iron(III)-catalyzed propargyl alcohol dehydration enables the synthesis of conjugated enynes in good to excellent yields with a large substrate scope and excellent stereoselectivity (only Z-isomers).
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Key Words
ID: J54-Y2012-1440
