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CuI/DMPAO-Catalyzed N-Arylation of Acyclic Secondary Amines

Yu Zhang, Xinye Yang, Qizheng Yao* and Dawei Ma*

*School of Pharmacy, China Pharmaceutical University, Nanjing 21009, China, Email:,

Y. Zhang, X. Yang, Q. Yao, D. Ma, Org. Lett., 2012, 14, 3056-3059.

DOI: 10.1021/ol301135c


The use of DMPAO as a ligand enables copper-catalyzed coupling of aryl halides with aliphatic acyclic secondary amines to take place under relatively mild conditions and at low catalyst loading.

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Discovery of N-(Naphthalen-1-yl)-N'-alkyl Oxalamide Ligands Enables Cu-Catalyzed Aryl Amination with High Turnovers

J. Gao, S. Bhunia, K. Wang, L. Gan, S. Xia, D. Ma, Org. Lett., 2017, 19, 2809-2812.

CuI/Oxalic Diamide Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amines

W. Zhou, M. Fan, J. Yin, Y. Jiang, D. Ma, J. Am. Chem. Soc., 2015, 137, 11942-11945.

Key Words

Ullmann Coupling, Aryl Amines

ID: J54-Y2012-1940