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Stereoselective Alkene Isomerization over One Position

Casey R. Larsen and Douglas B. Grotjahn*

*Department of Chemistry and Biochemistry, San Diego State University, San Diego, California 92182-1030, United States, Email: grotjahnsciences.sdsu.edu

C. R. Larsen, D. B. Grotjahn, J. Am. Chem. Soc., 2012, 134, 10357-10360.

DOI: 10.1021/ja3036477 (free Supporting Information)



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Abstract

A ruthenium complex is a very efficient catalyst for selective mono-isomerization of various multifunctional alkenes to afford E-products. Many reactions are complete within 10 min at room temperature. Even sensitive enols and enamides susceptible to further reaction can be generated. Very low catalyst loadings can be employed.

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Key Words

Isomerizations


ID: J48-Y2012-1980