S-Benzyl Isothiouronium Chloride as a Recoverable Organocatalyst for the Direct Reductive Amination of Ketones with Hantzsch Ester
Quynh Pham Bao Nguyen, Taek Hyeon Kim*
*School of Applied Chemical Engineering and Center for
Functional Nano Fine Chemicals, College of Engineering, Chonnam National
University, Gwangju 500-757, Republic of Korea, Email: thkim
chonnam.ac.kr
Q. P. B. Nguyen, T. H. Kim, Synthesis, 2012, 44, 1977-1982.
DOI: 10.1055/s-0031-1291125
Abstract
A direct reductive amination of ketones using the Hantzsch ester in the presence of S-benzyl isothiouronium chloride as a recoverable organocatalyst converts a wide range of ketones as well as aryl amines to the expected products in good yields.
see article for more examples
Key Words
S-benzyl isothiouronium chloride, reductive amination, ketones, aryl amines, hydrogen bond, Hantzsch ester, Organocatalysis
ID: J66-Y2012-2070
